The symptoms of immune hemolytic anemia include pale or yellowish skin color, tiredness or fatigue, fast heartbeat or heart rate, shortness of breath, enlarged spleen, and dark urine. The disease is diagnosed by performing several tests. The following indicate that the patient is suffering from the disease: Coombs’ test turning out positive direct or indirect; increased bilirubin levels; increased LDH level (LDH are enzymes that increase when the body is experiencing tissue damage); presence of hemoglobin in the urine; decreased serum haptoglobin level; increased reticulocyte count; and decreased hemoglobin and RBC count.
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