Eligible patients with a valid prescription for ADVAIR DISKUS (fluticasone propionate and salmeterol inhalation powder) or ADVAIR HFA (fluticasone propionate and salmeterol) Inhalation Aerosol who present this savings card at participating pharmacies will pay the first $10, and receive up to $50 off each 30-day prescription or refill of ADVAIR DISKUS or ADVAIR HFA applied to your out-of-pocket cost. This offer is good for up to 12 uses, and each 30-day supply counts as 1 use. Patient is responsible for applicable taxes, and remaining out of pocket cost, if any. This offer is limited to one per person and is nontransferable and cannot be combined with any other coupon, free trial or similar offer. No substitutions are permitted. Patients, pharmacists, and prescribers cannot seek reimbursement from health insurance or any third party for any part of the amount received by the patient through this offer. Offer must be presented along with a valid prescription for ADVAIR DISKUS or ADVAIR HFA at the time of purchase. Your acceptance of this offer must be consistent with the terms of any drug benefit plan provided to you by your health insurer. You agree to report your use of this coupon to your health insurer if required.
A twelve month study (Gaining Optimal Asthma ControL, GOAL), in 3416 adult and adolescent patients with persistent asthma, compared the safety and efficacy of Seretide versus inhaled corticosteroid (Fluticasone Propionate) alone to determine whether the goals of asthma management were achievable. Treatment was stepped up every 12 weeks until ** total control was achieved or the highest dose of study drug was reached. GOAL showed more patients treated with Seretide achieved asthma control than patients treated with ICS alone and this control was attained at a lower corticosteroid dose.
Whilst the use of inhaled steroids and long acting beta-adrenoceptor agonists (LABA) are recommended in asthma guidelines for the resulting improved symptom control,  concerns have been raised that salmeterol may increase the small risks of asthma deaths and this additional risk is not reduced with the additional use of inhaled steroids.  Other side effects from this drug combination may include increased blood pressure, change in heart rate, an irregular heartbeat, increased risk of osteoporosis, cataracts, and glaucoma.